Blog

The Many DMPK Challenges of Cancer Treatment ADCs

The Many DMPK Challenges of Cancer Treatment ADCs

Since German Nobel laureate Paul Ehrlich developed the concept of the “magic bullet” in 1907, researchers have chased the possibility relentlessly. Ehrlich’s immune response research proposed killing specific microbes without harming the body itself, a goal which...

QWBA vs. Mass Balance Studies

QWBA vs. Mass Balance Studies

Quantitative whole-body autoradiography (QWBA) and mass balance testing are equally important processes to gather data on a drug candidate’s absorption, distribution, metabolism, and excretion (ADME) properties.  While both QWBA and mass balance can give details...