Safety Pharmacology

Assessments to Advance Your Program

When you partner with WuXi AppTec, our team of experts will work with you to conduct in vitro and in vivo safety pharmacology studies to quickly and accurately assess the potential for toxicity across major therapeutic areas including CNS, cardiovascular, respiratory, gastrointestinal and renal systems. 

As part of our mission to seamlessly deliver high-quality data that enables high-quality drug candidates, you’ll have access to our world-class safety assessment center in Suzhou, China, where we invest in the most advanced technology for data acquisition and processing – and utilize the Ponemah® Software platform for data collection and assimilation. We also work with the International Conference on Harmonization International (ICH), complying with requirements and providing clarifications needed to advance your program successfully.

Non-GLP Cardiovascular Safety Screening Assays
  • Guinea pig QT assay
  • Rat telemetry studies
  • SHR studies for cardiovascular efficacy
  • EKG and indirect blood pressure in canines and Non-Human Primates (NHPs)
  • hERG assay


Safety Pharmacology Studies


  • Functional Observational Battery (FOB) studies in rats and mice
  • CNS system evaluation in mice, rats, canines and NHPs
  • Cardiovascular telemetry studies in conscious canines, NHPs and minipigs
  • Jacketed External Telemetry (JET) in conscious canines and NHPs
  • Respiratory system studies in conscious rats and mice (head-out plethysmographs), canines and NHPs
  • hERG assay
  • Gastrointestinal motility studies in rats and mice
  • Renal function in rats