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Scientific Posters

 

ACT, 2023

A Retrospective Analysis of Internal In Vitro Phototoxicity Data

ACT, 2023

Comparison of Routine Parameters of Tg.rasH2 Mice and Non-Tg.rasH2 Mice

EBF, 2023

Application of A Quick and Robust LC-MS/MS Method Quantitation of R-/S-Beta-Hydroxybutyrate in Rat Plasma

EBF, 2023

Bioanalysis of Endonuclease Cas9 in Plasma Conducing to Clarify CRISPR-Cas9-Mediated Development Using Immunocapture Followed with LC-MS/MS Screener Application

AAPS, 2023

Comparison of Branched DNA (B-DNA) and Reverse Transcription-Polymerase Chain Reaction (RT-qPCR) Method Validation for the Quantification of mRNA Therapeutics in Plasma

AAPS, 2023

Effect of pH on Metabolite Profiling and Identification of GalNAc Conjugated siRNA in In Vitro Metabolic System

AAPS, 2023

A Comprehensive Bioanalytical Strategy of In Vivo Studies for RNAi Therapeutics in Early Discovery

AAPS, 2023

Metabolite Identification of Nucleoside Analog Prodrugs in Biological Matrix by Derivatization Coupled with Radio-Detector and Mass Spectrometry

AAPS, 2023

Quantitative Analysis of GalNAc-siRNA Conjugates in Tissue Homogenate Using Two-Dimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry

AAPS, 2023

Research Strategy of Chiral PROTACs in Discovery Stage Based on Analysis Platforms of UPCC-MS/MS and UPLC-MS/MS

AAPS, 2023

Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control

AAPS, 2023

Study on the Permeability of Ophthalmic Tissues In Vitro

AAPS, 2023

Validation Of An In Vitro Cell-based Assay For The Detection Of Neutralizing Antibodies Against Adeno-associated Virus 9 In Cynomolgus Monkey

AAPS, 2023

Bioanalysis Of Endonuclease CAS9 In Plasma Conducing To Clarify Crispr-CAS9-Mediated Genome Engineering Using Immunocapture Followed With Lc-ms/ms Screener Application

AAPS, 2023

Development Of An Ultrasensitive qPCR Method To Identify And Quantify Point Mutation In Circulating Tumor DNA

AAPS, 2023

Evidence-Based Strategies for the Characterization of New Chemical Entity (NCE) In Vitro CYP and Non-CYP Enzyme Reaction Phenotyping at the Development Stage

ISSX, 2023

Development of a Convenient In Vitro Method for Predicting Metabolism and Disposition of Acrylamide Covalent Drugs in Humans

ISSX, 2023

Strategies for Enhancing Oral Exposure of Water-Insoluble Compounds

ISSX, 2023

Radiolabeled Mass Balance Studies in Preclinical Animals

ISSX, 2023

Novel Approach to Determine Plasma Protein Binding for Labile Compounds Using Equilibrium Dialysis

ISSX, 2023

Experimental Validation of the Reliability of Dilution Method for Plasma Protein Binding Assay in Human Plasma Using Commercial Compounds

ISSX, 2023

Establishment of the Relay Method for Low Turnover Compounds in Hepatocyte Stability Assays

ISSX, 2023

Development of a Plasma Stability Assay for Oligonucleotides

ISSX, 2023

Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control

ISSX, 2023

Plasma Protein Binding of Oligonucleotides Using Rapid Agarose Gel Electrophoretic Mobility Shift Assay

EuroTox, 2023

Incidence of Common Arrhythmias in Bama Minipigs of Stand-Alone Safety Pharmacology and General Toxicology Studies

EuroTox, 2023

Comparison of the Dermal Histopathological Structure Between the Bama and Göttingen Minipigs

EuroTox, 2023

In Vivo Phototoxicity Studies in Rats and Guinea Pigs with Systemic Administration

EuroTox, 2023

An Evaluation of Detection Sensitivity and Pharmacokinetic Profile for Conscious Telemetered Cynomolgus Monkeys

White Papers

Developing a Convenient In Vitro Method for Predicting Metabolism and Disposition of Acrylamide Covalent Drugs in Humans

Detect and Characterize In Vitro PCCs of Non-Cleavable ADCs Using a New LC-HRMS Method

Unknowns are Unacceptable

Pharmacokinetic Bioanalysis Strategies for Antibody-Drug Conjugates (ADCs)
Based on LC-MS

The BAMA MINIPIG in Toxicology

Comparison Between Magnetic Bead and Membrane Immunoaffinity Purification Methods for the Measurement of Monoclonal Antibody in Rat Serum

Internal Standard (IS) Variation Case Studies: Emerging From Three Common IS Challenges

Metabolite Identification (MetID): A Critical Step in Drug Discovery and Development

ICH M10 Guidance: Harmonization and Modification to Bioanalytical Method Variation

The 2019 FDA Guidance’s Implications for Immunogenicity Assessment

Bridging Preclinical and Clinical Assays for Biologics Development –Challenges and Considerations for Phase I Trials

Webinars

Designing Extractable/Leachable Studies for Drugs and Biologics

Preclinical Oligonucleotide Drug Development: Insight from DMPK

The Strategies and Methods of in-vitro ADME Characterizations of ADCs

DMPK Strategies for Oligonucleotide Therapeutics

Hot Topics and Challenges in Drug Development

DMPK Challenges and Strategies for Developing Oligonucleotide Drugs

DMPK Strategies for Successful Clinical Translation

DMPK Addressing Safety Testing of Drug Metabolites (MIST) in Drug Development

DMPK Optimization of Proteolysis-Targeting Chimeras

ICP-MS

Bioanalysis in Gene and Cell Therapy

Expediting Biologics Drug Development: Strategies to Accelerate Preclinical Development Timelines

AAPS – The Unique Bioanalytical Needs of New Modalities

Brochures

Safety Assessment Services Brochure

Bioanalytical Services

Safety Assessment Services Brochure

Oligonucleotide Drugs

Safety Assessment Services Brochure

Antibody Drug Conjugate

Safety Assessment Services Brochure

Proteolysis Targeting Chimera

Safety Assessment Services Brochure

Peptide

Safety Assessment Services Brochure

Safety Assessment Services

Safety Assessment Services Brochure

Peptide-Drug Conjugate

Service Catalog

Drug Metabolism and Pharmacokinetics

Presentations

Preclinical Strategy and Considerations for Gene Therapies