Preclinical Testing

Testing Toxicity to Advance to Phase I Clinical Trials

Testing Toxicity to Advance to Phase I Clinical Trials

Preclinical research teams enter each drug testing project with the same hope – that the drug will meet all the safety requirements in order to advance to phase I clinical trials in humans.  In laboratory experiments, scientists will test their ideas for new...

Good Communication Essential To Successful Preclinical Testing

Good Communication Essential To Successful Preclinical Testing

For both large and small drug development companies, good communication displayed throughout the preclinical testing process is essential to success. Project leaders who exhibit great awareness, flexibility and communication skills can’t be undervalued in the timely...

Grand Opening of New R&D Center in China

Grand Opening of New R&D Center in China

The Nanjing Branch of the DMPK Business Unit Begins Operation Grand Opening On May 24, 2021, the Nanjing Branch of the DMPK business unit of WuXi AppTec’s Laboratory Testing Division opened for business in a grand fashion. The event attracted many presenters,...

ICH M10: Preview New Bioanalytical Method Validation Guidance

ICH M10: Preview New Bioanalytical Method Validation Guidance

The International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) is in the process of revising M10, a multidisciplinary guideline that governs bioanalytical method validation. Drugs need to contain the correct...

Pathologists Can Move Your Drug Development Program Forward

Pathologists Can Move Your Drug Development Program Forward

Pathologists examine the causes and mechanisms of diseases and, in the world of drug development, that means collecting, processing and analyzing tissue for toxicity. Histotechnologists fix tissue samples onto slides, stain them to distinguish types of cells and cell...

WuXi AppTec Grows Biomarker Capabilities with Quanterix

WuXi AppTec Grows Biomarker Capabilities with Quanterix

The newest partnership between Quanterix and WuXi AppTec Laboratory Testing Division (LTD) integrates industry-leading instruments and reagents with world-class laboratory and technical staff to form the co-developed Simoa Joint Lab in Shanghai. Starting in 2021, drug...

How DMPK Lead Optimization Mitigates Risk and Conserves Resources

How DMPK Lead Optimization Mitigates Risk and Conserves Resources

Lead optimization in the world of drug development is a multifaceted process. It is a crucial part of discovery pharmacology and toxicology, as such, is used to identify and advance the most promising drug compounds. First and foremost, lead optimization aims to...

WuXi AppTec & Quanterix Simoa Joint Lab Opening Ceremony

WuXi AppTec & Quanterix Simoa Joint Lab Opening Ceremony

On April 23, 2021, Quanterix and WuXi AppTec's Laboratory Testing Division (LTD) inaugurated the "Joint Laboratory for Biomarker Clinical Analysis" at WuXi AppTec's headquarters in Shanghai. The event attracted more than 50 guests including Dr. Steve Yang, WuXi AppTec...