Genetic &
in vitro Toxicology

The genetic toxicology division performs both non-GLP and GLP genotoxicity assessments for regulatory filings as well as screening assays for safety lead optimization. Utilizing industry-leading instruments, technologies and expertise, our genetic toxicologists and study directors are committed to presenting rapid, high-quality data that can inform of potential damage during subsequent stages of development.

Genetic Toxicity Screening Assays
+ Mini Ames assay
+ Microwell micronucleus assay

Genetic Toxicity GLP Assays
+ Ames assay
+ in vitro chromosomal aberration assay
+ in vitro micronucleus assay
+ Mouse lymphoma assay
+ in vivo micronucleus assay in rodents

GLP or non-GLP in vitro Cytotoxicity Assays for Biocompatibility
+ MTT assay
+ MEM elution assay
+ Agarose overlay assay
+ Neutral red uptake assay
+ Relative growth rate method
+ Direct contact method

GLP or non-GLP in vitro Phototoxicity Assay
+ 3T3 NRU phototoxicity assay
+ GLP in vitro electrophysiology assay
+ hERG assay