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AAPS, 2023

Development Of An Ultrasensitive qPCR Method To Identify And Quantify Point Mutation In Circulating Tumor DNA

ACT, 2023

A Retrospective Analysis of Internal In Vitro Phototoxicity Data

ACT, 2023

Comparison of Routine Parameters of Tg.rasH2 Mice and Non-Tg.rasH2 Mice

ISSX, 2023

Plasma Protein Binding of Oligonucleotides Using Rapid Agarose Gel Electrophoretic Mobility Shift Assay

EuroTox, 2023

Incidence of Common Arrhythmias in Bama Minipigs of Stand-Alone Safety Pharmacology and General Toxicology Studies

EuroTox, 2023

Comparison of the Dermal Histopathological Structure Between the Bama and Göttingen Minipigs

ISSX, 2023

Establishment of the Relay Method for Low Turnover Compounds in Hepatocyte Stability Assays

ISSX, 2023

Development of a Plasma Stability Assay for Oligonucleotides

ISSX, 2023

Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control

ISSX, 2023

Radiolabeled Mass Balance Studies in Preclinical Animals

ISSX, 2023

Novel Approach to Determine Plasma Protein Binding for Labile Compounds Using Equilibrium Dialysis

ISSX, 2023

Experimental Validation of the Reliability of Dilution Method for Plasma Protein Binding Assay in Human Plasma Using Commercial Compounds

AAPS, 2023

Evidence-Based Strategies for the Characterization of New Chemical Entity (NCE) In Vitro CYP and Non-CYP Enzyme Reaction Phenotyping at the Development Stage

ISSX, 2023

Development of a Convenient In Vitro Method for Predicting Metabolism and Disposition of Acrylamide Covalent Drugs in Humans

ISSX, 2023

Strategies for Enhancing Oral Exposure of Water-Insoluble Compounds

AAPS, 2023

Research Strategy of Chiral PROTACs in Discovery Stage Based on Analysis Platforms of UPCC-MS/MS and UPLC-MS/MS

AAPS, 2023

Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control

AAPS, 2023

Study on the Permeability of Ophthalmic Tissues In Vitro

AAPS, 2023

A Comprehensive Bioanalytical Strategy of In Vivo Studies for RNAi Therapeutics in Early Discovery

AAPS, 2023

Metabolite Identification of Nucleoside Analog Prodrugs in Biological Matrix by Derivatization Coupled with Radio-Detector and Mass Spectrometry

AAPS, 2023

Quantitative Analysis of GalNAc-siRNA Conjugates in Tissue Homogenate Using Two-Dimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry

AAPS, 2023

Validation Of An In Vitro Cell-based Assay For The Detection Of Neutralizing Antibodies Against Adeno-associated Virus 9 In Cynomolgus Monkey

AAPS, 2023

Comparison of Branched DNA (B-DNA) and Reverse Transcription-Polymerase Chain Reaction (RT-qPCR) Method Validation for the Quantification of mRNA Therapeutics in Plasma

AAPS, 2023

Effect of pH on Metabolite Profiling and Identification of GalNAc Conjugated siRNA in In Vitro Metabolic System

EuroTox, 2023

In Vivo Phototoxicity Studies in Rats and Guinea Pigs with Systemic Administration

EuroTox, 2023

An Evaluation of Detection Sensitivity and Pharmacokinetic Profile for Conscious Telemetered Cynomolgus Monkeys

WRIB, 2022

Development of a Multiplex RT-qPCR Method to Quantify mRNA Transcript

WRIB, 2021

Development of a Sensitive and Robust qPCR Method to Quantify siRNA Against HBV in Human Plasma

WRIB, 2021

Method Validation for the Evaluation of Plasma Protein Binding of LGX818 and MEK162 by Rapid Equilibrium Dialysis and LC-MS/MS

AAPS, 2021

Determination of Modified Thymidine Phosphorylase Concentration and its Activity in Mouse Serum by LC-MS/MS