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Scientific Posters

AAPS, 2025

Application of Lecithin (PL90) and Poloxamer 188 in SLC Transporter-Mediated Drug Interaction Studies

AAPS, 2025

Development and Implementation of a Ferret Venous Catheterization Model for Pharmacokinetic Studies

AAPS, 2025

Enhancing Oral Bioavailability in Preclinical Dog PK Studies Using Ball Milling Technology

AAPS, 2025

Establishment of a High-Throughput Screening and Characterization Platform for Covalent Inhibitor Drugs

AAPS, 2025

Human Pharmacokinetics Prediction for Trastuzumab Using Scaling and Two-Compartment Modeling with B-hFcRn Mice PK Data

AAPS, 2025

Sensitive LC-MS/MS Method for Cationic Ligand-Conjugated siRNA Therapeutics

ACT, 2025

Establishing Reference Ranges for Lymphocyte Subsets in Healthy Bama Minipigs for Immunotoxicity Assessment

ACT, 2025

Establishing the Internal hERG Safety Margin Threshold Using a Series of Reference Drugs to Support the Integrated QTc Risk Assessment

SPS, 2025

Statistical Power Analysis of Standard Cardiovascular Safety Pharmacology Studies in Telemetry Implanted Dogs and Nonhuman Primates

SPS, 2025

Diurnal Variations Analysis of the Cardiovascular Parameters in Cynomolgus Monkeys of Stand-Alone Safety Pharmacology Studies

ISSX, 2025

Substrate and System-Dependent Activation of CYP2B6

SOT, 2025

Method Validation for the Reactive Oxygen Species (ROS) Assay for Photoreactivity

ISSX, 2025

The Strategy for UGT Enzyme Phenotyping

ISSX, 2025

Strategies for Enhancing Oral Drug Bioavailability Inter Individual Variability and Manual Control of Gastric pH in Fasting Monkeys

ISSX, 2025

Establishment of a Novel Funnel Model for Evaluating Blood-Brain Barrier Penetration in Vitro

ISSX, 2025

Pharmacokinetic Comparison of Pemetrexed Administered via Lumbar Intrathecal vs. Cisterna Magna Intubation in Sprague-Dawley Rats

ISSX, 2025

Probing Drug and Metabolite Covalent Binding with a Non-Radiolabeled Method Osimertinib as an Example

ISSX, 2025

Propylene Glycol Dose-Dependent Hemolysis in Intravenous Formulations Thresholds and Mitigation Strategies in Beagle Dogs

ISSX, 2025

Is the Direct or Indirect Method the Ideal One for Evaluation of Blood to Plasma Ratio

ISSX, 2025

Measurement of Phosphoinositide (PIP) Metabolism via Derivatization-Based Liquid Chromatography-Tandem Mass Spectrometry

ISSX, 2025

Novel Rat Intrathecal Catheterization Model for Direct Antisense Oligonucleotide (ASO) Drug Delivery to the Central Nervous System

ISSX, 2025

Fast Biomimetic High-Performance Liquid Chromatography Method for Evaluating Human Plasma Protein Binding

ISSX, 2025

In Vitro Metabolic Stability Evaluation of Peptides

ISSX, 2025

Intrathecal Administration Techniques for CNS Delivery in Non-Human Primates Practical Tools for Oligonucleotide Drug Pharmacokinetics

ISSX, 2025

Exploring Cremophor-Induced Allergic Reactions In Beagle Dogs Mitigation Strategies For Injectable Formulations

ISSX, 2025

Application of Lecithin (PL90) and Poloxamer 188 in Permeability and P-GP BCRP Mediated Drug Interaction Studies in Caco-2 Cells

ISSX, 2025

Desorption Strategies in Peptide Formulation Preparation Insights from In Vitro Adsorption (Non-Specific Binding) Assessment Experiments

ISSX, 2025

Development of in vitro Methods to Assess Inhibition Potential in Nine Recombinant UGT Isozymes

ISSX, 2025

Effect of Bovine Serum Albumin on Permeability, Efflux Ratio and Recovery of Compounds in MDCKII-MDR1 Monolayers

BDRP, 2025

Investigation of Embryo-Fetal Development Toxicity of Cyclophosphamide in Mice

WRIB, 2025

LCMS Bioanalysis Of Oligonucleotides: Optimization Of Alkylamines And Fluorinated Alcohols As Solvent Modifiers

WRIB, 2025

Method Qualification For Immunophenotyping Of Cd137+ T Cell Subsets In Human Whole Blood By Flow Cytometry Using Contrived Samples

WRIB, 2025

Method Validation Of Classical And Alternative Pathway Complement Activity In Human Serum

WRIB, 2025

Comparison Of Different Assay Kits For Dog Serum Parathyroid Hormone (PTH) Measurement

WRIB, 2025

A Quantitative Analysis Method For Intracellular Proteins (IKAROS/AIOLOS) By Flow Cytometry To Support Pharmacodynamic Studies Of Targeted Protein Degraders

SOT, 2025

Spontaneous Lesions Associated with Test Article-Unrelated Deaths in Repeated Dose Mouse Studies

SOT, 2025

Validation of Fluorescence In Situ Hybridization Method in Mouse – With a Novel Staining Strategy

SOT, 2025

Validation of the Flow Cytometry Based Pig-a Gene Mutation Assay in Rats

SOT, 2025

A Retrospective Analysis of the Potential Associated Factors of Procedure-Related Findings in Intrathecal Injection Studies

SOT, 2025

Spontaneous Ocular Lesions Observed in Laboratory Animals

SOT, 2025

Case Study-Strategy of Follow-up Assays in Genotoxicity

SOT, 2025

Comparison of Systemic Exposure in Pregnant and Non-Pregnant Sprague-Dawley Rats

SOT, 2025

Early siRNA Formulation Screening Using Lumbar Intrathecal Infusion via Cannulation vs. Free-Hand Method – A Comparison for Preliminary Toxicity Detection Using Behavioral Tests and Tissue Distributions

SOT, 2025

Establishing the Preclinical Immunotoxicity Reference Based on Immunophenotyping Data in Bama Minipigs

SOT, 2025

Evaluation of the Impact of the Use of Slide Imaging in the Histopathological Evaluation of Toxicology Studies

OLDER POSTERS

White Papers

Optimizing DART Assessments for Regulatory Success & Emerging Modalities

Detect and Characterize In Vitro PCCs of Non-Cleavable ADCs Using a New LC-HRMS Method

Pharmacokinetic Bioanalysis Strategies for Antibody-Drug Conjugates (ADCs)
Based on LC-MS

The BAMA MINIPIG in Toxicology

Developing a Convenient In Vitro Method for Predicting Metabolism and Disposition of Acrylamide Covalent Drugs in Humans

Comparison Between Magnetic Bead and Membrane Immunoaffinity Purification Methods for the Measurement of Monoclonal Antibody in Rat Serum

Internal Standard (IS) Variation Case Studies: Emerging From Three Common IS Challenges

Metabolite Identification (MetID): A Critical Step in Drug Discovery and Development

ICH M10 Guidance: Harmonization and Modification to Bioanalytical Method Variation

The 2019 FDA Guidance’s Implications for Immunogenicity Assessment

Bridging Preclinical and Clinical Assays for Biologics Development –Challenges and Considerations for Phase I Trials

Webinars

Past Webinars

in association with

Bioanalytical Challenges and Strategies of T-cell Engager Therapeutics

Thursday, October 16, 2025

T-cell engager (TCE) therapeutics represent an exciting frontier in oncology and immunotherapy, but their complex structure and mechanism of action create unique challenges for bioanalysis. This webinar will provide an overview of the background of TCE therapeutics, followed by a deep dive into bioanalytical considerations across pharmacokinetics, immunogenicity (ADA and NAb) and biomarker analysis.

in association with

Peptide Therapeutics: Navigating Development with DMPK & Toxicology

Peptide therapeutics offer immense potential but present complex development challenges, particularly in oral formats. This expert-led presentation explores how integrated DMPK, bioanalytical, and toxicology strategies can address barriers to absorption, stability, and safety. Focusing on practical case examples and proven approaches; it highlights how thoughtful study design and cross-functional expertise can streamline development and reduce risk from early studies through clinical advancement.

WATCH NOW

in association with

Panel Discussion: Advancing Bioanalytical Method Development and Validation for Small Molecules in a Changing Regulatory Landscape

This session covers the current landscape of bioanalytical method development and validation for small molecules, including method development strategies, emerging technologies and validation best practices.

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Advancing In Vitro Metabolic Models and Metabolite Identification for Oligonucleotide Therapeutics

Oligonucleotide DMPK Research Strategy & In Vitro Metabolism Models

Optimizing DMPK Strategy for Peptide Drugs

Nervous System (CNS) Drug Delivery Techniques in Large Animals (Non-Rodents) Enhancing DMPK Research for Oligonucleotide Drugs

Discovery, Characterization, and Manufacture of Peptide Radiopharmaceuticals

Integrated bioanalytical strategy for LNP-mRNA products

Facilitating ADC Preclinical DMPK Research with An Integrated Bioanalysis Platform

Challenges and solutions in bioanalysis for oligonucleotide drugs

Overcoming Challenges in Precise Structural Identification of Target Metabolites

DMPK Strategies for Oligonucleotide Therapeutics

DPMK Strategies in the Preclinical Development of Antibody-Drug Conjugates

DMPK Strategies for Successful Clinical Translation

Hot Topics and Challenges in Drug Development

The Strategies and Methods of in-vitro ADME Characterizations of ADCs

ICP-MS

DMPK Addressing Safety Testing of Drug Metabolites (MIST) in Drug Development

DMPK Challenges and Strategies for Developing Oligonucleotide Drugs

Preclinical Oligonucleotide Drug Development: Insight from DMPK

Expediting Biologics Drug Development: Strategies to Accelerate Preclinical Development Timelines

DMPK Optimization of Proteolysis-Targeting Chimeras

Brochures

Opthamology Services Brochure

IND, Enabled

Bioanalytical Services

Proteolysis Targeting Chimera

Peptide

Oligonucleotide Drugs

Peptide-Drug Conjugate

Safety Assessment Services

Antibody Drug Conjugate

BAS GLP-1

PROTAC

Service Catalog

Drug Metabolism and Pharmacokinetics

Presentations

Check out our 15-minute presentation on the revolutionary impact of ADCs in targeted cancer therapy. Detailing their journey from conception to becoming a leading treatment modality, we highlight the significant bioanalytical challenges and regulatory milestones that shape ADC development.

What you will learn:

The components of ADCs and their roles in targeting and killing tumor cells
Bioanalytical details on PK, PD, immunogenicity, receptor occupancy and immunotoxicity studies
Analytical platforms and techniques
Challenges in ADC bioanalysis
Guidelines and strategies for biomarker bioanalysis

WATCH THE PRESENTATION